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KMID : 0376219810180020245
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Chonnam Medical Journal
1981 Volume.18 No. 2 p.245 ~ p.255
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Dual Phases of Positional Alcoholic Nystagmus in the Goats
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Abstract
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In unanesthetized goats fixed in recumbent position, ethyl alcohol (1.59/k9, B. W.) was injected intravenously, and position of the head were altered in various modes to elicite positional alcoholic nystagmus. Nystagmic reactions of the bilateral eyes were observed with naked eyes and was also recorded by means of nystagmographic technique to monitor their changes in temporal pattern. Influence of total destruction of bilateral vestibular apparatus upon the elicitation of the positional nystagmus was also observed, and the following results were obtained.
1. When 5´10 min. elapsed after administration of alcohol, rotation of the head to either direction (leftwards or rightwards) and rerotation to original (neutral) position elicited positional nystamus. Nystagmic direction was always contrary between the two eyes.
2. When rotation of the head was reversed to the opposite direction, nystagmic reaction was also reversed to the opposite direction.
3. The late phase in the nystagmic reaction (PAN II) as well as the early phase (PAN I) was well discriminated in this animals as was previously reported for man.
4. Total destruction of the bilateral vestibular apparatus abolished both the PAN I and PAN II .
These experimental results indicate that the positional alcoholic nystagmus reveals not only PAN I but also PAN II in this animal. Such a finding is in contrast to the previous reports in which PAN revealed only phase I in the experimental animals (such as rabbits, cats, dogs and rats).
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